HorsesPrefer Natural Flex Nutribites contain glucosamine, manganese, and chondroitin sulfate to help support normal joint health and function in horses. The apple-flavored tablets are very palatable, making them easy to feed, and they may be either mixed with food or given as a treat. Glucosamine is a natural supplement that is easily-absorbed by the body and is used to help maintain joint and connective tissue health and resiliency. It helps to prevent cartilage degeneration in horses suffering from arthritis. In osteoarthritis, the cushions surrounding each joint becomes stiff and thin. Glucosamine helps supply the materials necessary to rebuild the cushion. Chondroitin is added because its use has been shown to possibly increase the efficiency of glucosamine. Nutribites also utilize the health benefits of manganese, a trace mineral that is found in tiny amounts in the body, mostly in bones, the liver, pancreas, and kidneys. Manganese helps the body form bones and connective tissue. It plays a role in calcium absorption, as well as fat and carbohydrate metabolism and blood sugar regulation. It is also necessary for normal brain and nerve function. Manganese is important because it is a component of the antioxidant enzyme, superoxide dismutase (SOD), which fights free radicals, naturally-occurring substances found in the body that can damage cell membranes and DNA. They play a role in aging, as well as the development of many other health conditions, including cancer and heart disease. Antioxidants, such as SOD, helps to neutralize free radicals and reduce, or help prevent, some of the damage they cause.